Opeoida petider och autism

Detta är en länklista för allt jag hittar kring Opeoida peptider och autism/ADD/ADHD

Neurozym


NCBI/Pubmed

Conclusion:Autism spectrum disorders are a diverse group of disorders caused by a complex interplay between genetic and environmental components. There is a range of indications that alterations in the intestinal microbiota in the gut might contribute to the disorder in a substantial number of individuals. Probiotics can be useful to restore the microbial balance in the intestine, to relieve gastrointestinal problems and to attenuate immunological abnormalities. Whether the use of probiotics by children with autism can lead to improvements in behaviors needs to be established in well-controlled trials with sufficient group sizes. Important for these trials is the choice of the bacterial strains, as effects of probiotic bacteria can be highly strain specific.
The Potential Role of Probiotics in the Management of Childhood Autism Spectrum Disorders

Gluten
Conclusion: Celiac disease is markedly overrepresented among patients presenting with ADHD. A gluten-free diet significantly improved ADHD symptoms in patients with celiac disease in this study. The results further suggest that celiac disease should be included in the ADHD symptom checklist.
http://www.ncbi.nlm.nih.gov/pubmed/?term=Association+of+Attention-Deficit%2FHyperactivity+Disorder+and+Celiac+Disease%3A+A+Brief+Report

Casein och gluten 
Our results suggest that dietary intervention may positively affect developmental outcome for some children diagnosed with ASD" Whiteley P. et al. The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders. Nutritional Neuroscience. 2010 Apr;13(2):87-100. http://www.ncbi.nlm.nih.gov/pubmed/20406576


Other sources

This study indicates that consumption of certain foods, such as milk and gluten, may contribute to ADHD in children who lack the enzyme that breaks down proteins like casein, a component of milk--which also helps in the formation of cheese. Interestingly, when children who lack this enzyme eat foods that require the enzyme to properly digest proteins like casein, their brains experience an opium-like effect, which might explain at least some of the spaciness and impaired attention these kids exhibit. http://www.celiac.com/articles/21800/1/ADHD-Caused-by-Digestive-Disorder/Page1.html

THEORY BEHIND THE GLUTEN AND CASEIN-FREE DIET
Conclusion: The molecular structure of the partially undigested proteins, known as peptides, resemble opiates. It is thought that such peptides have an effect much like opiates (ie. morphine, heroin) in the brain and nervous system. From this premise it follows that long-term exposure to these opiate peptides can have many damaging effects on the developing brain and also affects behavior, just as any narcotic would. The opioid peptides involved are identified as casomorphines from casein, and gluten exorphines and gliadorphin from gluten."
http://celiacdisease.about.com/od/commoncomplicationsofcd/a/Gluten-And-Adhd.htm
http://www.autism-help.org/intervention-casein-gluten-free.htm


 Gluten
Conclusion: The data indicate that ADHD-like symptomatology is markedly overrepresented among untreated CD patients and that a gluten-free diet may improve symptoms significantly within a short period of time. The results of this study also suggest that CD should be included in the list of diseases associated with ADHD-like symptomatology." Niederhofer H. Association of Attention-Deficit/Hyperactivity Disorder and Celiac Disease: A Brief Report. The Primary Care Companion for CNS Disorders. 2011; 13(3):PCC.10br01104. http://jad.sagepub.com/content/10/2/200.short 
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Gluten
Lahat E. et al. Prevalence of celiac antibodies in children with neurologic disorders. Pediatric Neurology. 2000 May;22(5):393-6.
http://archinte.jamanetwork.com/article.aspx?articleID=215079
http://diyhpl.us/~bryan/papers2/paperbot/A%20Preliminary%20Investigation%20of%20ADHD%20Symptoms%20in%20Persons%20With%20Celiac%20Disease.pdf
http://www.nejm.org/doi/full/10.1056/nejmoa021687
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